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62. Future Course of New Lethal Avian Flu Outbreak in China Can be Predicted April 7, 2013


Will H7N9 Follow Limited Course of SARS or Longer Course of H1N1 Pandemic? Does a Potential Pandemic Need to Be Prevented, and Can it Be? Is the competitive withholding of information on H7N9 rational or ethical?

LONDON, April 7, 2013. Bioradar UK Ltd. and Replikins Ltd. today announced that when the full H7N9 virus genomic sequences from the first lethal and surviving human cases of the current outbreak of H7N9 are available for analysis their Bioradar Replikins FluForecast®software will be able to determine within 24 hours the likely future course of the H7N9 outbreak as the data did successfully for SARS in 2003 and for H1N1 in 2009.

FluForecast® data had previously analyzed the virus genomic sequences in the 2003 SARS coronavirus outbreak and in the 2009 H1N1 influenza virus pandemic (1-4) and successfully predicted their respective courses. The genomic sequences of the SARS virus in cases in 2003 and those of H1N1 were published promptly worldwide; the sequences for H7N9 are not being published promptly, in part because of admitted competition between governments, pharmaceutical firms, and research institutes to who will be first to make a vaccine (5). It is here submitted that where from hundreds of thousands to millions of lives are possibly at stake, this is a dumb and unethical place to have a competition (6). Unethical for obvious reasons; dumb because the more scientists have the data available to pursue different methods rapidly to a safe and effective vaccine, the better the chance of successful limitation or prevention of the possible pandemic.

Furthermore, BioRadar UK Ltd. and Replikins Ltd. can produce an effective non-biologic synthetic vaccine tailored to the current H7N9 outbreak within seven days as they did with H5N1 (1). All of the above is possible because scientists at Bioradar, UK. Ltd and its affiliate Replikins, Ltd. have discovered a genomic structure, and a technology related to virus rapid replication, infectivity, and lethality named Replikins.

The Replikins genomic technology permits:

  1. The prediction of the arrival, geographic location, lethality, and the course of an infection, with an accuracy (p<0.001) recognized by the UN FAO (1)
    • The Replikins genomic software predicted the H1N1 outbreak and pandemic of 2009 by an increase in the genomic Replikin®Count in 2008, one year in advance of the pandemic, as reported by CNN's Dr. Sanjay Gupta (1-3)
    • The increase in genomic Replikins has been counted and seen by 3D X-ray diffraction in the first real-time tracking of structural genomic changes from pre-pandemic through pandemic clinical states (1).
  2. The production of tailored influenza vaccines in 7 days, by solid phase synthesis.
    • Replikins synthetic vaccines, shipped freeze dried, have been shown to be effective against H5N1 and Taura Syndrome viruses (1,2,4).
    • Replikins, Ltd. has developed both a cross-strain ReplikinsTransFlu®Vaccine and a specific H7N9 Replikins vaccine available for further testing.

Contact sbogoch@replikins.com. tel 646-320-5910

References:

  1. Nature Precedings. Bogoch et al, doi:10.1038/npre.2012.6952.1 (see also seven additional Nature Precedings Publications, Bogoch 2011-2012. http://precedings.nature.com/users/549471c7b195af1864d2f1b1996f60642.
  2. www.replikins.com
  3. Dr. Sanjay Gupta of CNN Reports on Replikins (www.replikins.com)
  4. Jackwood et al. Avian Diseases 53(4): 613-617, 2009

 

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Dr. Sanjay Gupta of CNN reports on Replikins

Synthetic flu vaccine option?

2009 report on Replikins and the potential of synthetic vaccine technology to improve on traditional vaccine approaches.