Replikins - Synthetic Vaccines

The biochemistry of rapid replication


Home
Overview
Videos
Background
The Science
Contact Us
Replikins Press

	Pioneering the development and rapid production of synthetic vaccines
	Recent News
	"Sitting Ducks" No Longer: Advance Flu Warning Permits Creation of Replikins Custom Synthetic Flu Vaccine in Animals November 10, 2011 Animals and humans no longer need to be "sitting ducks," oblivious to and unprepared for emergent infectious disease outbreaks. Rather than being caught off-guard by mass influenza outbreaks, UK-based biotech firm BioRadar Ltd. can successfully analyze the concentration and structure of the genomic Replikins in 'scout' viruses isolated from initial cases up to one year or longer, which provides advance warning of, and the ability to respond to the coming specific outbreaks Read more UN Food and Agriculture Organization (FAO) discussion of Replikins Sept. 8, 2011 SOURCE: DVM NEWSMAGAZINE Rome - A major resurgence of the H5N1 Highly Pathogenic Avian Influenza through a mutant strain of the virus is spreading through Asia and global leaders are warning against a possible marriage between the highly lethal bird flu strain and the highly infectious H1N1. Replikin Counts of the two virus strains are rising simultaneously-an occurrence that has not been seen before, warns the United Nations Food and Agriculture Organization (FAO). Read more FAO Warnings Follow Rise in Replikins Count for Both H5N1 and Swine Flu (H1N1); Replikins Synthetic TransFlu™ Vaccine Tested U.N. Food and Agriculture Organization Warns of 'Possible Major Resurgence' of Avian Flu (H5N1) in Asia and a New Vaccine-Evading Strain in Vietnam and China. Replikin Counts of the two virus strains are rising simultaneously-an occurrence that has not been seen before, warns the United Nations Food and Agriculture Organization (FAO). Read more Marked Rise in Replikin Counts in H5N1 Influenza Virus Localized to Lethality Gene p B1. September 15, 2011 Bogoch, Samuel and Bogoch, Elenore. Marked Rise in Replikin Counts in H5N1 Influenza Virus Localized to Lethality Gene p B1 ... Available from Nature Precedings http://dx.doi.org/10.1038/npre.2011.6420.1(2011) Prediction of specific virus outbreaks made from the increased concentration of a new class of virus genomic peptides, replikins Bogoch, Samuel and Bogoch, Elenore. Prediction of specific virus outbreaks made from the increased concentration of a new class of virus genomic peptides, replikins.. Available from Nature Precedings http://dx.doi.org/10.1038/npre.2011.6279.1(2011) Swine Flu: It's Back. Doctors Shocked by Spread of Virus and its Severity The Independent December 11, 2010 - "H1N1 virus returns, already claiming lives of 10 British adults with early signs that illness has spread to other European countries. The Swine flu virus that swept the world last year causing a global health emergency has returned to claim the lives of 10 adults in the UK in the past six weeks" Read more

	FluForecast™		Synthetic Vaccines
	The current spread of bird flu has drawn attention to the need for improved public health measures to predict, prevent and counter both natural and man-made emerging epidemic threats. Our FluForecast™ software technology has shown that an increase in Replikin Count™ peptide quantities precedes observed epidemics. In addition, after an epidemic has run its course, there is a decline in Replikin Count™ peptide quantities. Previously, no quantitative virus protein changes were known which correlate with, let alone predict, influenza epidemics such as the current H5N1 Bird Flu, or indicate their cessation. Advance specific warning, made possible by our discovery of a biochemistry of rapid replication, now allows time a) for public health measures to be instituted, and b) for an early start on synthetic vaccine development.		Recent outbreaks of SARS, H5N1 (bird flu) and H1N1 (swine flu) have increased awareness of the need for rapid vaccine development in response to emerging viral threats. Replikins software-driven technology allows for earlier development of vaccine candidates, as well as rapid prototyping and production of the vaccines that emerge from early clinical trials. Replikins are a new class of peptides whose increase in concentration in virus proteins (Replikin Count™ peptide quantities) is associated with rapid replication. Subtypes of these peptides are consistently present in a wide range of rapidly-replicating viruses, pointing the way towards synthesis of vaccine candidates.

New Videos

International H1N1 Swine Flu Conference The International Swine Flu Conference addressed best practices to prepare for, respond to, and survive a pandemic.
Synthetic flu vaccine option? Possibility to create a H1N1 synthetic flu vaccine. CNN's Dr. Sanjay Gupta reports.
ABC Boston discusses Bogoch Replikins ABC Boston discusses Replikins synthetic peptide H1N1 vaccine, produced in 7 days, is available now for testing worldwide.